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BPS BPS-Pharmacotherapy Exam Syllabus Topics:

BPS Pharmacotherapy (Part1 and Part2) Sample Questions:

1. The Randomized Aldactone Evaluation Study (RALES) yielded the following results:
* Placebo death rate: 386/841
* Spironolactone death rate: 284/822
Given these data, which of the following is the relative risk reduction for death with spironolactone, in comparison with placebo?

A) 24%
B) 45%
C) 31%
D) 11%

2. Which statement best describes current recommendations on postnatal corticosteroids in neonatal Broncho pulmonary dysplasia?

A) High-dose dexamethasone is routinely and strongly recommended.
B) Combination of dexamethasone and hydrocortisone long-term therapies is advised.
C) Early, low-dose, short-course hydrocortisone therapy may be beneficial.
D) Late and long-term hydrocortisone therapy may be warranted.

3. Administration of a marketed drug to a patient for an off-label indication without approval from a local IRB is permissible in which of the following situations?

A) The patient's physician considers that the risk/benefit ratio favors the use of the drug.
B) The drug is administered under a protocol sponsored by an NIH grant.
C) The drug is administered on the request of the patient or the patient's representative.
D) The patient's physician has filed a Notice of Claimed Investigational Exemption for a New Drug with the FDA.

4. A clinical trial is being designed to evaluate the efficacy of an intermediate-acting niacin preparation in a population with regard to amelioration of coronary artery disease risk.
Bioethical considerations would restrict recruitment of subjects with poorly controlled diabetes mellitus, recent gastroduodenal ulcer disease, or hyperuricemia. Which principle would consider these patients to be ineligible for enrollment?

A) Beneficence
B) Justice
C) Autonomy
D) Equipoise

5. Which of the following is a risk factor for the development of multidrug resistance in pathogens that cause nosocomial pneumonia?

A) Current hospitalization for the past 3 days
B) Antimicrobial therapy implemented 6 months ago
C) Hemodialysis initiated 2 days ago
D) Home infusion therapy that includes antibiotics

Solutions: